Neutrophil Associated Abs-994
Test info
Support the diagnosis of immune neutropenia in various autoimmune disorders.
TRALI (Transfusion Related Acute Lung Injury), SLE (Systemic Lupus Erythematosus), RA (Rheumatoid Arthritis), Myasthenia gravis, Felty's syndrome, drug-induced neutropenia
Specimen
Immediatley following collection, mix sample by gently inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Spin within two (2) hours of sample collection
Gold serum separator (SST) tube
- Allow sample to clot
- Spin
- Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum, within two (2) hours of sample collection
Ambient (preferred) - 5 days
Refrigerated - 5 days
Frozen - 1 year
- Grossly hemolysis
- Grossly lipemia
- Icteric samples
Performance
Bead-Based Multiplex Immunoassay
Clinical and Interpretive info
Negative
Neutrophil associated antibodies may occur in primary autoimmune neutropenia in both adults and children as an isolated hematological disorder. The antibodies could occur as a secondary phenomenon in various autoimmune disorders including systemic lupus erythematosus, rheumatoid arthritis, myasthenia gravis, Felty's syndrome, and drug-induced neutropenia.