Alpha-galactose, IgE-13480

Test info

  
Alpha-galactose, IgE
  
13480
  
LAB13480
  
FGA13
  
Alpha Gal
Alpha galactose, IgE
Galactose
Galactose-alpha-1,3-galactose (Alpha Gal) IgE
  
Immunoglobulin E, total
Alpha-Gal
  

Measurement of IgE to galactose alpha-1,3-galactose (α-Gal sIgE) is used in the differential diagnosis of α-Gal mediated allergy. There are two distinct forms of this allergy: the first is an immediate-onset anaphylaxis observed following intravenous infusion of Cetuximab, a monoclonal antibody against epidermal growth factor receptor, and the second is a delayed-onset allergy or anaphylaxis that occurs several hours following consumption of red meat. Bites from certain ticks, such as the Lone Star Tick in the United States, have been implicated in the development α-Gal allergy. Furthermore, α-Gal may be helpful in elucidating the allergen responsible in patients initially diagnosed as having ‘idiopathic’ anaphylaxis or urticaria.

Specimen

  
Serum
  
  
0.2 mL
  

Immediatley following collection, mix sample by inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Gold serum separator (SST) tube

  
  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  3. Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum
  
  

Ambient (preferred) - 14 days

Refrigerated - 14 days

Frozen - 3 months

Freeze/thaw cycles - stable x3

  
  • Lipemic specimens

Performance

  
LabCorp (650001): R-LC
  
Mo - Sa
  
5 days
  

ImmunoCAP® 

Clinical and Interpretive info

  

Negative <0.1 kU/L

Billing

  
86008
  
Yes
  
  
Result 73837-7

Tracking

  
03/27/2019
  
12/21/2023
  
12/21/2023