Alpha-galactose, IgE-13480

Test info

  
Alpha-galactose, IgE
  
13480
  
LAB13480
  
FGA13
  
Alpha Gal
Alpha galactose, IgE
Galactose
Galactose-alpha-1,3-galactose (Alpha Gal) IgE
  
Immunoglobulin E, total
Alpha-Gal
Beef IgE
Pork IgE
Lamb IgE
  

Measurement of IgE to galactose alpha-1,3-galactose (α-Gal sIgE) is used in the differential diagnosis of α-Gal mediated allergy. There are two distinct forms of this allergy: the first is an immediate-onset anaphylaxis observed following intravenous infusion of Cetuximab, a monoclonal antibody against epidermal growth factor receptor, and the second is a delayed-onset allergy or anaphylaxis that occurs several hours following consumption of red meat. Bites from certain ticks, such as the Lone Star Tick in the United States, have been implicated in the development α-Gal allergy. Furthermore, α-Gal may be helpful in elucidating the allergen responsible in patients initially diagnosed as having ‘idiopathic’ anaphylaxis or urticaria.

Specimen

  
Serum
  
  
0.2 mL
  

After collection, mix by gently inverting 5 times

  

Spin

  

Gold serum separator (SST) tube

  
  
  1. Allow sample to clot
  2. Spin
  3. Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum, within two (2) hours of sample collection
  
  

Ambient (preferred) - 14 days
Refrigerated - 14 days
Frozen - 3 months

Freeze/thaw cycles - stable x3

  
  • Lipemic specimens

Performance

  
LabCorp (650001): R-LC
  
Mo - Sa
  
5 days
  

Solid phase immunoassay

Clinical and Interpretive info

  

Negative <0.1 kU/L

Billing

  
86008
  
Yes
  
  
Result 73837-7

Tracking

  
03/27/2019
  
11/15/2019
  
12/16/2021