Inflammatory Bowel Disease (IBD)

Alphabetical Test listing

Inflammatory Bowel Disease (IBD)-13541

  
Inflammatory Bowel Disease (IBD)
  
13541
  
LAB13541
  
IBD
  
Bowel disease
Crohn's disease
Ulcerative colitis
  

Rule out Crohn's disease and ulcerative colitis

  
Serum
  
  
1.5 mL
  
0.7 mL
Submitting the minimum volume does not allow for repeat testing
  

Spin

  

Gold serum separator (SST) tube

 

  
  

Spin and separate

  
  

Refrigerated

  
  • Bacterial contamination
  • Hemolysis
  •  Lipemia
  
LabCorp Burlington (164830): R-LC
  
2 - 5 days
  

Atypical ANCA: Indirect fluorescent antibody (IFA)

Saccharomyces cerevisiae, IgA and IgG: Enzyme immunoassay (EIA)

  

Saccharomyces cerevisiae, IgA                                                   Negative: < 20.0

Saccharomyces cerevisiae, IgG
Equivocal:    20.1 - 24.9
positive:   ≥ 25.0

Atypical antineutrophil cytoplasmic antibodies                        Negative: < 1:20

  

IgA and IgG antibody testing for S. cerevisiae is useful adjunct testing for differentiating Crohn's disease and ulcerative colitis.  Nearly 80% of Crohn's disease patients are positive for either IgA or IgG.  In ulcerative colitis, less than 15% are positive for IgG, and less than 2% are positive for IgA.  Fewer than 5% of healthy controls are positive for either IgG or IgA antibody, and no healthy controls had antibody for both.  The atypical ANCA pattern has been observed in a significant percentage of patients with ulcerative colitis, primary sclerosing cholangitis, and autoimmune hepatitis.

  
86671 x 2
86256
  
Result 49503-6
  
04/08/2019
  
05/20/2019
  
02/23/2021