Striational Antibodies

Alphabetical Test listing

Striational Antibodies-994

Test name:

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

Anti-Skeletal Muscle IgG Antibodies
Anti-Striated Antibody
Anti-Striated Muscle Antibody
Muscle (Skeletal) Antibodies
Myoid Antibody
Skeletal Muscle Antibodies

Useful for:

Recommended for differential evaluation of neuromuscular junction diseases including myasthenia gravis (MG).

Specimen type:

Serum

Collection container:

Gold serum separator (SST) tube

Volume:

1.0 mL

Minimum volume:

0.5 mL

Collection instructions:

Immediately following collection, thoroughly mix sample by gently inverting 5 times

Processing instructions:

Allow sample to clot for a minimum of 30 minutes
Spin

Transport container:

Gold serum separator (SST) tube

Alternate collection container:

Red serum vial/tube, 5 mL

Alternate processing instructions:

Allow sample to clot
Spin
Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum.

Alternate transport container:

Transfer vial/tube with cap - 12mL (LabCorp)

Transport and stability:

Ambient (preferred) – 14 days

Refrigerated – 14 days

Frozen – 14 days

Reason for rejection:

Plasma
Contaminated specimens
Severe lipemia
Severe hemolysis

Performing lab:

Labcorp (160184): R-NX

Days set up:

Mo - Fi

TAT:

2 - 4 days

Method:

Immunofluorescence (IF)

Reference ranges:

Negative: <1:100

Clinical information:

Autoantibodies directed against the contractile elements of striated muscle are found in 30% of adult patients with myasthenia gravis and 80% of those with thymoma. These antibodies may also be detected in patients with: Lambert-Eaton myasthenic syndrome, small-cell lung carcinoma, breast carcinoma, patients treated with D-penicillamine, bone marrow transplant recipients having graft-versus-host disease, and autoimmune liver disorders.

CPT codes:

86255

Date created:

01/14/2022

Revised date:

07/11/2023

Review date:

01/14/2022