Cytokeratin 18 by IHC

Alphabetical Test listing

Cytokeratin 18 by IHC-12376 - Technical only, 12379 - Technical & interpretation

  
Cytokeratin 18 by IHC
  
12376 - Technical only, 12379 - Technical & interpretation
  
LAB12376
LAB12379
  
CK18
  

All IHC stains will include a positive control tissue

  
  • CK 18 is one of the most commonly found intermediate filaments in epithelial cells
  • This cytokeratin is expressed in single layer ductal/glandular epithelial cells, throughout the body (is not present in squamous epithelium)
  • This marker is often used to identify endometrial cancers
  • CK 18 frequently is present with CK8; mutations of these genes associated with these cytokeratins increase susceptibility to liver disease (cryptogenic cirrhosis)
  
Tissue
  

Submit a formalin-fixed, paraffin-embedded tissue

  

Formalin-fixed, paraffin-embedded (FFPE) tissue block

  

FFPE tissue section mounted on a charged, unstained slide

  

Ambient (preferred)

  
  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
  
AHL - Immunohistochemistry
  
Mo - Fr
  
1 - 2 days
  

Immunohistochemical staining and microscopic examination

  

If requested, an interpretive report will be provided

  

Specifications

  • Antibody recognizes human cytokeratin 18 intermediate filament protein, 45 KDa

Staining pattern

  • Cytoplasmic based

  
88342 - 1st stain
88341 - each additional stain
  
10/30/2017
  
10/18/2018
  
10/02/2020