Pro B-type natriuretic peptide

Alphabetical Test listing

Pro B-type natriuretic peptide-7095

  
Pro B-type natriuretic peptide
  
7095
  
LAB7095
  
PBN
  
N terminal proBNP
NT Pro BNP
ProBNP (B-type natriuretic peptide)
  

Aids in the diagnosis of congestive heart failure

  

It is recommended that patients abstain from any biotin containing supplement for 12 - 24 hours prior to blood draw. Biotin is commonly found in hair, skin and nail supplements and multivitamins.

  
Lithium heparin (Li hep) plasma
  
  
0.5 mL
  

Spin

  

Lt green plasma separator (PST)

  
Serum
EDTA plasma
  

Gold

  1. Ensure that complete clot formation has taken place prior to centrifugation. If specimen is centrifuged before a complete clot forms, the presence of fibrin may cause erroneous results.
  2. Spin

Red

  1. Ensure that complete clot formation has taken place prior to centrifugation. If specimen is centrifuged before a complete clot forms, the presence of fibrin may cause erroneous results.
  2. Spin and separate

Lavender

        Spin and separate

  

Gold serum separator (SST) tube

False bottom plasma/serum transport vial/tube (AHL)

  

Refrigerated (preferred) - 6 days

Ambient - 3 days

Frozen (-20°C) - 24 months

  
Hennepin Health/HCMC (NTPBNP): R-HM
  
Daily
  
1 - 2 days
  

Electrochemiluminescence Immunoassay (ECLIA)

  

< 50 yrs old: < 450 pg/mL

50 -75 yrs:   < 900 pg/mL

> 75 yrs:      < 1800 pg/mL

All individuals regardless of age with an estimated GFR 60 mL/min: < 1800 pg/mL

  

NT-proBNP values less than 300 pg/mL have a 99% negative predictive value for excluding congestive heart failure.  A cutoff of 1200 pg/mL for patients with an eGFR <60 yields a diagnostic sensitivity and specificity of 89% and 72% for acute congestive heart failure.  A diagnostic NT-proBNP cutoff of 900 pg/mL has been suggested in adults 50-75 years of age in absence of renal failure.

  
Biotin interference alert - see Patient preparation
  
83880
  
Yes
  
  
11/30/2018
  
10/12/2020
  
02/14/2020