Y chromosome microdeletion

Alphabetical Test listing

Y chromosome microdeletion-994

Test name:

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Tests included:

Five common Y chromosome microdeletions:

AZFa
AZFb
AZFc
AZFbc
AZFabc

Useful for:

Aids in determining the cause of azoospermia or oligospermia
Helps predict effectiveness of assisted reproductive technologies in men with Y chromosome microdeletions

Specimen type:

EDTA whole blood

Collection container:

Lavender (EDTA), 4mL

Volume:

2.0 mL

Minimum volume:

1.0 mL

Collection instructions:

Immediatley following collection, mix sample by inverting 8 - 10 times to prevent clotting

Processing instructions:

Submit tube unspun

Transport container:

Lavender (EDTA), 4mL

Alternate specimen type:

ACD whole blood

Alternate collection container:

Yellow ACD (A or B)

Alternate transport container:

Yellow ACD (A or B)

Transport and stability:

Refrigerated (preferred) – 1 month

Ambient – 1 week

Frozen - NO

Performing lab:

ARUP (2001778) via LabCorp (009985): R-NX

Days set up:

Varies

TAT:

8 - 10 days

Method:

Polymerase Chain Reaction/Electrophoresis

Reference ranges:

See report

Clinical information:

Y chromosome microdeletions are typically characterized by azoospermia, severe to moderate oligospermia, or abnormal sperm morphology/motility in men with a normal physical evaluation. Assisted reproductive techniques are contraindicated for men carrying AZFa, AZFb, AZFbc or AZFabc microdeletions, which are classically associated with spermatogenic failure.

Preauthorization:

This test may require preauthorization from the insurance provider. Check the payer guidelines and, if needed, obtain the pre-authorization prior to sample collection.

CPT codes:

81403

Other billing information:

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medical billing request form along with the sample.

Complete and submit the form to notify us of the need for Allina Health Laboratory to bill insurance for Molecular testing performed
All information requested is required in order for your request to be completed

Molecular Medicare billing request

Date created:

10/12/2020

Revised date:

12/18/2023

Review date:

12/18/2023