Angelman syndrome (AS) by FISH

Alphabetical Test listing

Angelman syndrome (AS) by FISH-4280F

Test name:

Test number:

4280F

Excellian order number:

LAB4280F

Abbreviation:

CYG

Alternate names:

UBE3A
Chromosome 15q11.2 deletion / duplication

Useful for:

Detects deletions and duplications involving the UBE3A gene on 15q11.2 within the Angelman syndrome (AS) critical region. Reciprocal duplication of this region is associated with chromosome 15q11-q13 duplication syndrome

Specimen type:

Whole blood

Collection container:

Dk green

Volume:

5.0 mL

Minimum volume:

2.0 mL

Collection instructions:

If both chromosome and FISH tests are ordered, only 1 tube is needed.

Cytogenetics specimen collection

Transport container:

Dk Green top (Na Heparin) tube - NO gel

Alternate specimen type:

Cord blood

Alternate specimen volume:

2.0 mL

Transport and stability:

Ambient

Do not heat or freeze

Performing lab:

AHL - Cytogenetics: X

Days set up:

Mo - Fr

TAT:

14 days

Method:

Fluorescence in situ Hybridization (FISH)

Reference ranges:

Interpretive report

CPT codes:

88271 x2
88273
88275
88230 - Culture (if appropriate)

Subject to medical necessity (Y/N):

Yes

LCD/NCD:

Medical necessity

Date created:

08/17/2015

Revised date:

09/01/2015