SF3B1 mutation analysis

Alphabetical Test listing

SF3B1 mutation analysis-994

  
SF3B1 mutation analysis
  
994
  
LAB994
  
MSO
  
SF3B1 gene sequencing
  
EDTA whole blood
  
  
5 mL
  
2 mL
  

Submit entire specimen - do not spin

  

Lavender (EDTA), 4mL

  
EDTA bone marrow
  

Lavender (EDTA), 4mL

  

Refrigerated - <72 hours

Ship same day if possible

  
NeoGenomics
  
Varies
  
10 days
  

RT-PCR and bi-directional sequencing of exons 14-17 of the SF3B1 gene

  

An interpretive report will be provided

  

SF3B1 mutations occur in 10-15% of CLL patients and serve as independent predictors of shortened time to treatment and poorer overall survival in CLL. Mutations are also detected in approximately 28% of MDS and 19% of myelodysplastic/myeloproliferative neoplasms. In MDS/MPN, most mutations were found in refractory anemia with ring sideroblasts (the RARS subtype).

  
81479
  
Yes
  
  
07/15/2019
  
07/22/2019