HLA-A29 Uveitis

Alphabetical Test listing

HLA-A29 Uveitis-994

  
HLA-A29 Uveitis
  
994
  
LAB994
  
MSO
  
A*29
A29
Birdshot Chorioretinopathy
Birdshot retinochoriodopathy
BSRC
HLA A29
HLA-A29
  

Birdshot chorioretinopathy (BSCR) is a rare form of autoimmune uveitis that can lead to severe visual impairment. Greater than 95% of patients diagnosed with BSCR carry the human leukocyte antigen (HLA)A*29 allele of the major histocompatibility complex (MHC). The MHC family of genes code for a highly variable set of cell surface glycoproteins (HLAs) that play a critical role in presenting antigens to T cell receptors to elicit an immune response.

  
EDTA whole blood
  
  
7.0 mL
  
3.0 mL
  

Lavender (EDTA), 10mL

  
  

Two (2) Lavender (EDTA), 4mL

  

Ambient (strict) – 7 days

Frozen – NO

Refrigerated - NO

  
1 week
  
  • Hemolysis
  • Clotted specimen
  
LabCorp (167390): R-NS
  
Tu, Th
  
3 - 7 days
  

Sequence-based typing (SBT), sequence-specific oligonucleotide probes (SSOP), and/or sequence-specific primers (SSP) as needed to obtain the required resolution.

  

See report

The presence of HLA A*29 alone is not sufficient for a diagnosis of Birdshot Chorioretinopathy. Many individuals with HLA A*29 do not have the disease and some patients with the disease do not have HLA A*29.

  
81381
  
01/08/2021
  
01/08/2021