CD31 by IHC

Alphabetical Test listing

CD31 by IHC-12376 - Technical only, 12379 - Technical & interpretation

  
CD31 by IHC
  
12376 - Technical only, 12379 - Technical & interpretation
  
LAB12376
LAB12379
  
Anti-human endothelial cell
  

All IHC stains will include a positive control tissue

  
  • CD31 is a very sensitive and specific marker for endothelial differentiation, and is probably the first choice for vascular markers in studying benign and malignant vascular tumors
  • CD31 reacts weakly with mantle zone B cells, peripheral T cells, and neutrophils
  • In cryostat sections and blood smears, CD31 also labels megakaryocytes, platelets, and some plasma cells
  
Tissue
  

Submit a formalin-fixed, paraffin-embedded tissue

  

Formalin-fixed, paraffin-embedded (FFPE) tissue block

  

FFPE tissue section mounted on a charged, unstained slide

  

Ambient (preferred)

  
  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
  
AHL - Immunohistochemistry
  
Mo - Fr
  
1 - 2 days
  

Immunohistochemical staining and microscopic examination

  

If requested, an interpretive report will be provided

  

Specifications

  • Reacts with a glycoprotein found in endothelial cells and platelets

Staining pattern

  • Cytoplasmic and cell membrane-based staining

References

  1. De Young and Wick, et. al.: CD31: An Immunospecific Marker for Endothelial Differentiation in Human Neoplasms; Appl. Immunohistochem. 1:97-100, 1993.
  2. Longacre et. al.: CD31: A New Marker for Vascular Neoplasia; Advances in Anat. Pathol. 1:16-20, 1994.
  
88342 - 1st stain
88341 - each additional stain
  
06/16/2017
  
10/17/2018
  
10/02/2020