Anti-U3 RNP antibodies

Alphabetical Test listing

Anti-U3 RNP antibodies-994

Test name:

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

Anti-Fibrillarin Ab
Anti-U3 RNP Ab
Fibrillarin
U3 RNP

Useful for:

The U3-RNP (Fibrillarin) particle is thought to participate in the first step of preribosomal RNA processing. Anti-U3 RNP antibodies have been shown to be highly specific for patients with SSc.

Specimen type:

Serum

Collection container:

Gold serum separator (SST) tube

Volume:

1.0 mL

Minimum volume:

0.3 mL

Collection instructions:

Immediately following collection, mix sample thoroughly by gentle inversion, 5 times

Processing instructions:

Allow sample to clot for a minimum of 30 minutes
Spin to separate serum from the cells within one (1) hour of collection

Transport container:

Gold serum separator (SST) tube

Alternate collection container:

Red serum vial/tube, 5 mL

Alternate processing instructions:

Allow sample to clot for a minimum of 30 minutes
Spin to separate serum from the cells within one (1) hour of collection

Alternate transport container:

Transfer vial/tube with cap - 12mL (LabCorp)

Transport and stability:

Refrigerated (preferred) - 14 days

Ambient - 7 days

Frozen - 60 days

Freeze/thaw cycles - stable x1

Specimen retention time:

One (1) week post testing

Reason for rejection:

Grossly hemolyzed
Bacterial contamination
Lipemic specimen
Icteric specimen
Non-serum specimen types

Performing lab:

LabCorp (520019): R-NX

Days set up:

Daily

TAT:

14 - 21 days

Method:

RIPA Gel Radiography

Reference ranges:

Negative

CPT codes:

86235

Date created:

02/19/2021

Review date:

12/21/2023