Thrombin time

Alphabetical Test listing

Thrombin time-510

  
Thrombin time
  
510
  
85670.2
  
TT
  
TT
  
Sodium citrate (Na cit) whole blood (3.2%)
  
  
4.5 mL
  
2.7 mL
  

Do not over or underfill tube as the ratio of anticoagulant to whole blood is critical.

  
  1. Process Platelet Poor Plasma (P.P.P) following the linked instructions.
  2. Coag – how to prepare a specimen for special coagulation testing
  3. Separate plasma into two (2) 1 mL aliquots, label as "NaCi Plasma P.P.P"
  4. Freeze immediately

STAT requests only:

Send whole blood sample in original collection container with STAT courier.

Must be tested within 4 hours of collection.

  

Routine:

Two (2) Microcentrifuge vial/tubes in a Snap cap conical vial/tube and cap (Beaker sites)

                             

Two (2) Coagulation specimen transport vial/tube  (all other sites)

                                     

STAT:

Lt blue Sodium citrate (NaCit)

  

Routine:

Frozen (strict)

Refrigerated - NO

Ambient - NO

Stat:

Ambient - 4 hours

  
  • Greiner tubes are not acceptable
  • Hemolysis
  • Patient on heparin > 1.0 IU/mL.
  • Incorrect volume
  • Exceeds standard testing time
  • Incorrectly labeled or mislabeled
  • Clotted
  • Plasma samples not completly frozen
  
AHL - Coagulation: W
  
Daily
  
1 day
  

Clot based assay

  

<20 sec

  

Prolongation of the thrombin time indicates:

  • An abnormality of fibrinogen
    • Qualitative; dysfibrinogenemia
    • Quantitative congenital: hypofibrinogenemia or afibrinogenemia
    • Quantitative acquired: DIC, fibrinolysis, liver disease
  • The presence of antithrombins
    • Therapeutic: heparin, hirudin, argatroban
  
85670
  
No
  
11/30/2001
  
10/20/2020
  
02/18/2020