Dabigatran-
As of October 21, 2024, this test has been discontinued. There is no alternative test available.
Test info
Pradaxa®
Measurement of drug level in order to monitor therapeutic level and/or diagnose under-dosage or potential toxicity.
Specimen
Lt blue Sodium citrate (NaCit) - 2.7mL
If the patient has a hematocrit >55, a specially prepared Lt blue Sodium citrate (NaCit) tube must be used in place of the standard Lt blue Sodium citrate (NaCit) tube.
Do not over or under fill the tube as the ratio of anticoagulant to whole blood is critical for accurate results
Immediatley following collection, mix sample thoroughly by gentle inverting 8 - 10 times, to prevent clotting
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Process Platelet Poor Plasma (P.P.P).
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Transfer plasma into a Transfer vial/tube with cap - 12mL (LabCorp) and apply a spot label "NaCit Plasma P.P.P"
Immediately following collection, thoroughly mix sample by gently inverting 5 times
1. Spin within 2 hours of sample collection
2. Transfer plasma to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as plasma
Ambient (preferred) - 7 days
Refrigerated - 14 days
Frozen - 14 days
Freeze/thaw cycles - stable x3
- Hemolyzed specimens
- Patient on heparin > 1.0 IU/mL
- Specimen exceeds standard testing time
- Unlabeled or mislabeled specimen
- Clotted specimen
- Over/under filled tube (incorrect volume)
Performance
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)