Anti thrombin lll activity-621

Test info

  
Anti thrombin lll activity
  
621
  
85300.0
  
AT3
  
Antithrombin
ATIII
  

Since the first report of a hereditary deficiency of AT III and its consequences in 1965, AT III has been considered an important parameter in spontaneous thromboembolic disorders. The hereditary deficiency, either quantitative or qualitative, is less common than the acquired deficiency. An acquired AT III deficiency has been described in DIC, septic shock, nephrotic syndrome, liver disease and in L-asparaginase treatments.

 

Specimen

  
Sodium citrate (Na cit) plasma
  

Two (2) Lt blue Sodium citrate (Na Cit) - 2.7mL tubes

If the patient has a hematocrit >55, a specially prepared Lt blue Sodium citrate (NaCit) tube must be used in place of the standard Lt blue Sodium citrate (NaCit) tube.

Hematocrit-Anticoagulant adjustments

  
2.0 mL
  
1.5 mL
  
  • Do not over or under fill tube as the ratio of anticoagulant to whole blood is critical

Coag – tube fill guidelines

  • Immediatley following collection, mix sample by gentle inversion 3 - 4 times to prevent clotting
  
  • Process Platelet Poor Plasma (P.P.P)

Coag – how to prepare a specimen for special coagulation testing

  
  

Frozen (strict) - 2 weeks

Refrigerated - NO

  
  • Improper label (unlabeled or mislabeled)
  • Improper anticoagulant
  • Improperly filled tube
  • Hemolysis
  • Clotted specimen
  • Delay in transport
  • Improper storage/transport temperature
  • Patients on heparin >1.0 IU/mL
  • Plasma samples not completely frozen

Performance

  
AHL - Coagulation/Special Coagulation: V
  
Varies: 1 - 2 times/wk
Available STAT
  
3 - 5 days
  

Chromogenic

Clinical and Interpretive info

  
Age Range in %
0 - 5 days 40-95
6 - 30 days 48-108
1 – 6 mo 70-125
>7 mo 80-135

Billing

  
85300

Tracking

  
11/30/2001
  
03/19/2024
  
01/12/2024