Risperidone & metabolite

Alphabetical Test listing

Risperidone & metabolite-1880

Test name:

Test number:

1880

Excellian order number:

82542.1

Abbreviation:

RSP

Alternate names:

9-Hydroxyrisperidone
Risperdal

Useful for:

Therapeutic drug management

Specimen type:

Serum

Collection container:

Red serum vial/tube - 5 mL

Volume:

3.0 mL

Minimum volume:

0.6 mL

Collection instructions:

Trough levels are most reproducible

Processing instructions:

Allow sample to clot
Spin within two (2) hours of sample collection
Transfer serum to a Serum/plasma transfer vial/tube (MedTox), labelled as serum

Transport container:

Serum/plasma transfer vial/tube (MedTox)

Alternate specimen type:

Heparin plasma (acceptable, but not preferred)

Alternate collection container:

Dk green heparin (Li or Na), no gel

Alternate processing instructions:

Spin within two (2) hours of sample collection
Transfer plasma to a Serum/plasma transfer vial/tube (MedTox), labelled as the appropriate plasma type

Transport and stability:

Refrigerated (preferred)

Ambient (OK) - 3 days

Frozen (OK)

Reason for rejection:

Gel-barrier tubes are not recommended

Performing lab:

MedTox Laboratories (757): R-MX

Days set up:

Tu, We, Th, Fr, Sa, Su

TAT:

5 - 7 days

Method:

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Reference ranges:

Expected steady state concentrations of risperidone and 9-hydroxyrisperidone (combined total) in patients receiving recommended daily dosages:

Risperidone + 9 - OH: 10 - 120 ng/mL

CPT codes:

G0480

Subject to medical necessity (Y/N):

Yes

LCD/NCD:

Medical necessity

Date created:

01/02/2003

Revised date:

12/28/2023

Review date:

12/28/2023