Peripheral Nervous System Demyelinating Neuropathy, Autoimmune Evaluation, Serum

Alphabetical Test listing

Peripheral Nervous System Demyelinating Neuropathy, Autoimmune Evaluation, Serum-994

  
Peripheral Nervous System Demyelinating Neuropathy, Autoimmune Evaluation, Serum
  
994
  
LAB994
  
MSO
  
Anti-MAG
Distal Acquired Demyelinating Symmetric Neuropathy (DADS)
IgM Neuropathy
Paratin Neuropathy
Anti-CNTN1
  

Evaluating patients with a suspected immune-mediated demyelinating peripheral neuropathy

  

For optimal antibody detection, specimen collection is recommended to occur before starting immunosuppressant medication or intravenous immunoglobulin (IVIg) treatment.

  
Serum
  

Red serum vial/tube, 10 mL

  
3 mL
  
2 mL
  

Immediately following collection, thoroughly mix sample by gently inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  3. Transfer serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum
  

Screw cap transfer vial/tube (Mayo T914)

  

Gold serum separator (SST) tube

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Gold serum separator (SST) tube

  

Refrigerated (preferred) - 28 days

Frozen - 28 days

Ambient - 72 hours

  
  • Gross hemolysis
  • Gross lipema
  • Gross iicterus
  
Mayo Clinic Laboratories (DMNES); R-NX
  
Monday - Sunday
  
5 - 8 days
  

DMNI: Technical Interpretation

CONCS: Cell-Binding Assay (CBA)

GQ1ES, IGG_D, IGM_D, IGG_M, IGM_M, IGDTS, IMDTS, IGMTS, IMMTS, MAGES: Enzyme-Linked Immunosorbent Assay (ELISA)

NF4FS: Flow Cytometry

 

  

See report

  

Demyelinating Neuropathy Evaluation Algorithm

  
83516 x5
83520
86255 x2
83520 x4 (if applicable)
  
05/02/2025
  
05/02/2025