B72.3 by IHC

Alphabetical Test listing

B72.3 by IHC-12376 - Technical only, 12379 - Technical & interpretation

Test name:

B72.3 by IHC

Test number:

12376 - Technical only, 12379 - Technical & interpretation

Excellian order number:

LAB12376
LAB12379

Tests included:

All IHC stains will include a positive control tissue

Useful for:

B72.3 reacts with a wide variety of adenocarcinomas, including ovarian, endocervix, endometrium, distal esophagus, stomach, colon, lung, breast, prostate, pancreas, and bile ducts
B72.3 does not react with hepatocellular carcinomas (0/20 cases)
Use B72.3 with panel in differentiating between malignant mesothelioma versus adenocarcinoma (see section on immunohistochemistry panels)

Specimen type:

Tissue

Processing instructions:

Submit a formalin-fixed, paraffin embedded tissue block

Transport container:

Formalin-fixed, paraffin embedded (FFPE) tissue block

Alternate transport container:

Tissue section mounted on a charged, unstained slide

Transport and stability:

Ambient (preferred)

Reason for rejection:

Unlabeled/mislabeled block
Insufficient tissue
Slides broken beyond repair

Performing lab:

AHL - Immunohistochemistry

Days set up:

Mo - Fr

TAT:

1 - 2 days

Method:

Immunohistochemical staining and microscopic examination

Reference ranges:

If requested, an interpretive report will be provided

Clinical information:

Specifications

Reacts with a high molecular weight glycoprotein designated tumor-associated glycoprotein-72 (TAG-72)

Staining patterns

Cytoplasmic and/or membrane/luminal staining

References

Long et. al.: Reactivity of B72.3 with Adenocarcinomas an Immunohistochemical Study of 476 cases, Cancer 72:2495-8, 1993.

CPT codes:

88342 - 1st stain
88341 - each additional stain

Date created:

05/09/2017

Revised date:

10/17/2018

Review date:

01/12/2024