Test name:  

Dementia, Autoimmune/Paraneoplastic Evaluation, Spinal Fluid

Test number:  

12687

Excellian order number:  

LAB12687

Abbreviation:  

DMC1

Alternate names:  

Cognitive decline
Cognitive impairment
DEMEC
Dipeptidyl aminopeptidase-like protein 6
Leucine-Rich Glioma Inactivated Protein-1 IgG

Tests included:  

Dementia, Interpretation, CSF
AMPA-R Ab CBA, CSF
Amphiphysin Ab, CSF
Anti-Glial Nuclear Ab, Type 1
Anti-Neuronal Nuclear Ab, Type 1
Anti-Neuronal Nuclear Ab, Type 2 Anti-Neuronal Nuclear Ab, Type 3
CASPR2-IgG CBA, CSF
CRMP-5-IgG, CSF
DPPX Ab IFA, CSF
GABA-B-R Ab CBA, CSF
GAD65 Ab Assay, CSF
GFAP IFA, CSF
IgLON5 IFA, CSF
LGI1-IgG CBA, CSF
mGluR1 Ab IFA, CSF
Neurochondrin IFA, CSF
NIF IFA, CSF
NMDA-R Ab CBA, CSF
Purkinje Cell Cytoplasmc Ab Type T 1
Purkinje Cell Cytoplasmic Ab Type 2

For reflex tests see algorithm listed on Clinical and Interpretive info tab.

Useful for:  

 

Investigating new onset dementia and cognitive impairment plus 1 or more of the following accompaniments in cerebrospinal fluid specimens:

• Rapid onset and progression
• Fluctuating course
• Psychiatric accompaniments (psychosis, hallucinations)
• Movement disorder (myoclonus, tremor, dyskinesias)
• Headache
• Autoimmune stigmata (personal history or family history or signs of diabetes mellitus,  thyroid disorder, vitiligo, poliosis [premature graying], myasthenia gravis, rheumatoid arthritis, systemic lupus erythematosus)
• Smoking history (20+ pack years) or other cancer risk factors
• History of cancer
• Inflammatory cerebrospinal fluid
• Neuroimaging findings atypical for degenerative etiology