Serotonin, serum

Alphabetical Test listing

Serotonin, serum-13377

Test name:

Serotonin, serum

Test number:

13377

Excellian order number:

LAB13377

Abbreviation:

SEROTONIN

Alternate names:

5-HT
5-Hydroxytryptamine

Useful for:

Serotonin measurement is used in conjunction with urinary 5-hydroxyindoleacetic acid (5-HIAA) and/or serum chromogranin A in the diagnosis of carcinoid syndrome.

Patient preparation information:

Monoamine Oxidase inhibitor drugs should be discontinued for at least one week prior to sampling since they test to increase the level of Serotonin

Specimen type:

Serum

Collection container:

Gold serum separator (SST) tube

Volume:

1.0 mL

Minimum volume:

0.5 mL
Submission of the minimum volume does not allow for repeat testing

Collection instructions:

Immediatley following collection, mix sample by gently inverting 5 times

Processing instructions:

Allow sample to clot for a minimum of 30 minutes
Spin within 30 minutes

Transport container:

Gold serum separator (SST) tube

Alternate collection container:

Red serum vial/tube, 5 mL

Alternate processing instructions:

Allow sample to clot
Spin
Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum, within 30 minutes of sample collection

Alternate transport container:

Transfer vial/tube with cap - 12mL (LabCorp)

Transport and stability:

Ambient (preferred) - 7 days

Refrigerated - 7 days

Frozen - 14 days

Freeze/thaw cycles: stable x2

Performing lab:

LabCorp Burlington (120204): R-LC

Days set up:

Tu - Fr, Su

TAT:

3 - 5 days

Method:

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Reference ranges:

Age (years)	Male (ng/mL)	Female (ng/mL)
0 - 12	46 - 321	22 - 271
13 - 60	31 - 207	31 - 207
>60	23 - 230	8 - 217

CPT codes:

84260

LOINC code:

Result 27057-9

Date created:

04/11/2019

Revised date:

05/30/2023

Review date:

05/30/2023