Metanephrines, fractionated, quantitative, 24-hour urine

Alphabetical Test listing

Metanephrines, fractionated, quantitative, 24-hour urine-13491

Test name:

Test number:

13491

Excellian order number:

LAB13491

Abbreviation:

METAUR

Tests included:

Metanephrine
Normetanephrine

Useful for:

Evaluation of catecholamine-secreting tumors of the adrenal medulla (pheochromocytomas) and extra-adrenal sympathetic and parasympathetic paragangliomas.

Patient preparation information:

No caffeine before or during collection
Monamine oxidase inhibitors should be discontinued at least one week prior to beginning collection

Specimen type:

Urine, 24-hr

Collection container:

24-hr urine collection container, no additive

Volume:

10 mL aliquot of a 24-hr collection

Minimum volume:

2.5 mL aliquot of a 24-hr collection

Collection instructions:

How to collect a 24-hr urine sample

Processing instructions:

Measure and record total 24-hour volume
Mix well
Transfer a 10mL aliquot to a Transfer vial/tube with cap - 12mL (LabCorp)

Transport container:

Transfer vial/tube with cap - 12mL (LabCorp)

Alternate collection container:

24-hr urine collection container with HCl

HCl is an acceptable preservative if required for a concurrently collected assay.

Transport and stability:

Ambient (preferred) - 14 days

Refrigerated - 14 days

Frozen - 14 days

Performing lab:

LabCorp Burlington (004234): R-LC

Days set up:

Mo - Fr

TAT:

3 - 6 days

Method:

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Reference ranges:

Normetanephrine

Age	Male	Female
0 – 8 years	48 - 229	48 - 200
9 – 12 years	80 - 384	71 - 296
13 – 20 years	105 - 405	90 - 315
21 – 30 years	110 - 553	95 - 449
>30 years	156 - 729	131 - 612

Metanephrine

Age	Male	Female
0 – 8 years	30 - 150	32 - 123
9 – 12 years	54 - 209	44 - 161
13 – 17 years	56 - 236	44 - 161
>17 years	58 - 276	36 - 209

CPT codes:

83835

LOINC code:

Normetanephrine, Ur: 21422-1
Normetanephrine, Ur, 24 hr 2671-6
Metanephrine, Ur: 19050-4
Metanephrine, U,24hr: 19049-6

Date created:

04/10/2019

Revised date:

06/12/2023

Review date:

05/30/2023