Prostate specific antigen by IHC

Alphabetical Test listing

Test name:

Test number:

12376 - Technical only, 12379 - Technical & Interpretation

Excellian order number:

LAB12376
LAB12379

Alternate names:

PSA
IHC

Useful for:

PSA is expressed by >99% of prostatic carcinomas (although poorly differentiated prostatic carcinomas may express this antigen weakly and/or focally)
PSA is a very durable antigen, even with prolonged formalin fixation
In vast majority of cases, prostatic acid phosphatase is not needed with PSA. However, we use prostatic acid phosphatase in weakly suspiciously PSA positive or PSA negative tumors in which prostatic origin is strongly suspected.

Specimen type:

Tissue

Processing instructions:

Submit processed tissue block or tissue section mounted on a charged, unstained slide

Transport container:

Formalin-fixed, paraffin embedded (FFPE) tissue block

Transport and stability:

Ambient (preferred)

Reason for rejection:

Performing lab:

AHL - Immunohistochemistry

Days set up:

Mo - Fr

TAT:

1 - 2 days

Method:

Immunohistochemical staining and microscopic examination

Reference ranges:

If requested, an interpretive report will be provided.

Clinical information:

All IHC stains will include a positive control tissue

Specifications:

PSA is a glycoprotein found in normal and neoplastic secretory and ductal prostatic epithelium

Staining pattern:

CPT codes:

88342 - 1 st stain
88341 - each additional stain

Date created:

08/08/2017

Revised date:

10/19/2018

Review date:

01/12/2024