Delta aminolevulinic acid, 24-hour urine
Delta aminolevulinic acid, 24-hour urine-994
Delta aminolevulinic acid, 24-hour urine
994
LAB994
MSO
ALA
ALA, delta, 24-hour urine
ALA Delta
Δ-Aminolevulinic Acid
ALA, delta, 24-hour urine
ALA Delta
Δ-Aminolevulinic Acid
Diagnose porphyrias
Urine, 24 hr
3 mL aliquot of a 24-hr collection
1.0 mL
How to collect a 24-hr urine sample
The 24-hour urine container must be kept refrigerated during the entire collection period
- Measure and record the 24-hour total volume.
- Mix well.
- pH must be <7.
- Transfer a 3 mL aliquot of the urine into a Amber screw-cap polypropylene frozen transport tube/vial - 4mL (LabCorp).
- Label the container with the patient's name, date, and time collection started and finished.
- The specimen should be protected from light and frozen immediately and maintained frozen until tested.
Frozen (protected from light) - 1 month
Refrigerated (protected from light) - 3 days
- Specimen not protected from light
- Use of preservative other than 30% acetic acid
- Use of sodium carbonate preservative
LabCorp Burlington (096354): R-NX
Mo, We, Fr
3 - 6 days
Column chromatography; Ehrlich reagent -spectrophotometry
0.5 - 5.1 mg/24 hours
Δ-ALA may be increased in attacks of acute intermittent porphyria, hereditary coproporphyria, and porphyria variegata; evaluation of certain neurological problems with abdominal pain; diagnosis of lead or mercury poisoning. Urinary Δ-ALA is not a sensitive indicator of lead poisoning in children because it does not increase until blood lead concentration is 40 μg/dL, well above the recommended level <15 μg/dL. ALA is increased also in tyrosinemia.Porphobilinogen and δ-aminolevulinic acid are the tests of choice for acute intermittent porphyria. Recently the molecular lesions have been identified in a severely affected homozygote with δ-aminolevulinate dehydratase deficient porphyria.
82135
Result 26974-6
06/06/2019
02/27/2024
02/27/2024