Smooth muscle actin by IHC

Alphabetical Test listing

Smooth muscle actin by IHC-12376 - Technical only, 12379 - Technical & interpretation

Test name:

Test number:

12376 - Technical only, 12379 - Technical & interpretation

Excellian order number:

LAB12376
LAB12379

Alternate names:

IHC
SMA
SMActin

Tests included:

All IHC stains will include a positive control tissue

Useful for:

SMA identifies smooth muscle cells and myoepithelial cells
SMA does not react with actin from fibroblasts, striated muscle, or myocardium
SMA is of limited use; MSA/HHF35 identifies more types of muscle actin

Specimen type:

Tissue

Processing instructions:

Submit a formalin-fixed, paraffin embedded tissue block

Transport container:

Formalin-fixed, paraffin embedded (FFPE) tissue block

Alternate transport container:

FFPE tissue section mounted on a charged, unstained slide

Transport and stability:

Ambient (preferred)

Reason for rejection:

Unlabeled/mislabeled block
Insufficient tissue
Slides broken beyond repair

Performing lab:

AHL - Immunohistochemistry

Days set up:

Mo - Fr

TAT:

1 - 2 days

Method:

Immunohistochemical staining and microscopic examination

Reference ranges:

If requested, an interpretive report will be provided

Clinical information:

Specifications

SMA reacts with a protein of the alpha smooth muscle isoform of actin

Staining patterns

Cytoplasmic based

CPT codes:

88342 - 1st stain
88341 - each additional stain

Date created:

05/02/2017

Revised date:

10/17/2018

Review date:

01/12/2024