Integrated 1 without NT

Alphabetical Test listing

Integrated 1 without NT-13688

Test name:

Test number:

13688

Excellian order number:

LAB13688

Abbreviation:

INT1ST

Alternate names:

Down syndrome
PAPP-A

Useful for:

Screening test for Open Spina Bifida (ONTD), Trisomy 21 (Down syndrome), and Trisomy 18 (Edwards syndrome).

Specimen type:

Serum

Collection container:

Gold serum separator (SST) tube

Volume:

3.0 mL

Minimum volume:

1.0 mL

Collection instructions:

Collect sample between 10.0 and 13.9 weeks of gestation.

Immediatley following collection, mix sample by gently inverting 5 times

Processing instructions:

1. Allow sample to clot for a minimum of 30 minutes
2. Spin within two (2) hours of sample collection

Pour-off/aliquoting is not advised

Transport container:

Gold serum separator (SST) tube

Required forms/information:

Maternal testing clinical information form

Transport and stability:

Ambient (preferred) - 7 days

Refrigerated - 14 days

Frozen - 14 days

Freeze/thaw cycles - stable x3

Reason for rejection:

Gross hemolysis
Gross lipemia

Performing lab:

LabCorp Burlington (017200): R-NX

Days set up:

Mo - Fr

TAT:

2 - 5 days

Method:

Chemiluminescent immunoassay

Clinical information:

This is a screening test. A positive result means that diagnostic testing may be offered to the pregnant woman to determine if a neural tube defect or chromosome abnormality is present.

Serum integrated screening requires two specimens: one collected in the first trimester and one in the second trimester.

This test number is for the first trimester portion of the test. Result interpretation will be provided only when the second trimester specimen is received and tested.

CPT codes:

84163

Date created:

06/14/2019

Revised date:

03/30/2022

Review date:

02/21/2024