ETV6/RUNX1 or TEL/AML or t(12;21), or amplification of RUNX1 (iAMP21) rearrangements, are recurring abnormalities in B-cell ALL. According to current NCCN B-ALL guidelines, ETV6/RUNX1 or TEL/AML or t(12;21) abnormalities are classified as a good cytogenetic risk factor, and amplification of RUNX1 (iAMP21) is classified as a poor cytogenetic risk factor.
This test can be ordered individually or as part of the B-cell ALL FISH Panels. See the panel tests for more details.
Sterile cup or tube
Place specimen in a sterile cup/tube with sterile culture medium, sterile Hanks Balance Salt Solution (HBSS) or sterile saline.
Submit entire specimen
Sterile specimen cup/tube
Touch prep slides
AHL Cytogenetics Oncology Request
Ambient
Fluorescence in situ hybridization (FISH)
Normal or Abnormal with interpretation