Integrated 2 without NT

Alphabetical Test listing

Integrated 2 without NT-13689

Test name:

Test number:

13689

Excellian order number:

LAB13689

Abbreviation:

INT2ND

Alternate names:

AFP-Maternal serum
Down syndrome

Useful for:

Screening test for open neural tube defects, Down syndrome, and Trisomy 18.

Specimen type:

Serum

Collection container:

Gold serum separator (SST) tube

Volume:

5 mL

Minimum volume:

3 mL

Collection instructions:

Serum integrated screening requires two specimens; one collected in the first trimester and one in the second trimester. This test number is for the second trimester portion of the test.
Collect between 15.0 and 21.9 weeks of gestation.

Immediatley following collection, mix sample by gently inverting 5 times

Processing instructions:

1. Allow sample to clot for a minimum of 30 minutes
2. Spin within two (2) hours of sample collection

Pour-off/aliquoting is not advised

Transport container:

Gold serum separator (SST) tube

Required forms/information:

Patient must have submitted a previous specimen in the first trimester for the Serum Integrated 1 test.
- Gestational age will be based on information provided with the first trimester specimen.
Maternal testing clinical information form

Transport and stability:

Ambient (preferred) - 7 days

Refrigerated - 14 days

Frozen - 14 days

Freeze/thaw cycles - stable x3

Reason for rejection:

Gross hemolysis
Gross lipemia

Performing lab:

LabCorp Burlington (017270): R-NX

Days set up:

Mo - Fr

TAT:

5 days

Method:

Chemiluminescent immunoassay

Clinical information:

A positive result means that diagnostic testing may be offered to the pregnant woman to determine if a neural tube defect or chromosome abnormality is present.

CPT codes:

86336
84702
82105
82677

Subject to medical necessity (Y/N):

Yes

LCD/NCD:

Medical necessity

Date created:

06/14/2019

Revised date:

03/30/2022

Review date:

02/21/2024