Neuromyelitis optica (NMO)/Aquaporin-4-IgG fluorescence-activated cell sorting (FACS) assay, serum

Alphabetical Test listing

Neuromyelitis optica (NMO)/Aquaporin-4-IgG fluorescence-activated cell sorting (FACS) assay, serum-12767

Test name:

Test number:

12767

Excellian order number:

LAB12767

Abbreviation:

NMOFS

Alternate names:

AQP
AQP4
Aquaporin
Devic's antibody
NMO
NMO-IgG optic neuritis antibody
Transverse myelitis antibody
Vision loss antibody

Tests included:

Testing will reflex to a titer, if indicated, at an additional charge

Useful for:

Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD)
Diagnosis of autoimmune AQP4 channelopathy
Diagnosis of neuromyelitis optica (NMO)
Distinguishing NMOSD from multiple sclerosis early in the course of disease

Specimen type:

Serum

Collection container:

Red serum vial/tube - 5 mL

Volume:

3.0 mL

Minimum volume:

2.0 mL

Processing instructions:

Allow sample to clot
Spin within two (2) hours of sample collection
Transfer serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum

Transport container:

Screw cap transfer vial/tube (Mayo T914)

Alternate collection container:

Gold serum separator (SST) tube

Alternate collection instructions:

Immediatley following collection, mix sample by gently inverting 5 times

Alternate processing instructions:

Allow sample to clot for a minimum of 30 minutes
Spin within two (2) hours of sample collection
Transfer serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum

Alternate transport container:

Screw cap transfer vial/tube (Mayo T914)

Transport and stability:

Refrigerated (preferred) - 28 days

Frozen - 28 days

Ambient - 72 hours

Performing lab:

Mayo Clinic Laboratories (NMOFS): R-MM

Days set up:

Mo, Tu, Th

TAT:

5 - 8 days

Method:

Flow Cytometry

Reference ranges:

Negative

CPT codes:

86053
86053 NMO/AQP4-IgG FACS titer (if appropriate)

Hospital EAP/charge code:

17026445
17028487 - Titer (if appropriate

Clinic EAP/charge code:

308605302
308605301 - Titer (if appropriate)

Date created:

08/31/2016

Revised date:

12/27/2023

Review date:

12/27/2023