Detection of gliadin antibodies aids in the diagnosis and monitoring of certain gluten-sensitive enteropathies, such as celiac disease and dermatitis herpetiformis
Immediatley following collection, mix sample by gently inverting 5 times
Gold serum separator (SST) tube
Ambient (preferred) - 7 days
Refrigerated - 14 days
Frozen - 14 days
Freeze/thaw cycles - stable x5
Fluoroenzyme Immunoassay EliA
0.0 - 10.0 U/mL
Negative: <7.0
Equivocal: 7.0 - 10.0
Positive: >10
A negative IgA result in an untreated patient does not rule out gluten-sensitive enteropathies, especially when associated with IgG gliadin antibodies. This can be explained by selective IgA deficiency, a relatively frequent finding in celiac disease. False-positives are possible as other gastrointestinal disorders are known to induce circulating antigliadin antibody, mainly Crohn disease, food protein intolerance, and postinfection malabsorption.