MYC by FISH [peripheral blood or bone marrow]
MYC by FISH [peripheral blood or bone marrow]-4280H (blood) or 4280G (bone marrow)
LAB4280G - CYTOGENETIC BONE MARROW STUDIES
Diffuse large B-cell lymphoma
FISH
Fluorescence in situ hybridization
High grade B-cell lymphoma
8q24
8q24 rearrangement
Identifying patients with MYC rearrangements.
- Differentiates diffuse Large B-cell lymphoma from High-grade lymphoma.
This test can be ordered individually or as part of a CLL full panel (see the individual panel test for more details).
Bone marrow aspirate:
Collect bone marrow aspirate in a sterile Sodium heparin (Na hep) syringe and transfer to a sterile vial/tube
- or -
Collect bone marrow aspirate in sterile syringe (non-heparinized) and transfer to a Dk green Sodium heparin (Na hep), no gel
Transfer aspirate from syringe to transport container.
Submit entire specimen unspun.
Sodium heparin (Na hep) whole blood
Touch prep slides
Bone marrow core:
submit in sterile tube filled with sterile culture medium, sterile Hanks Balance Salt Solution (HBSS) or sterile saline
Sodium Heparin (Na hep) whole blood:
Whole blood: 5 mL
Submit entire specimen
Bone marrow core:
Sterile vial/tube
Sodium Heparin (Na hep) whole blood:
- AHL Cytogenetics Oncology Request
Ambient
- Improper label (unlabeled or mislabeled)
- Wrong container (anticoagulant or solution)
- Delay in transport
- Improper storage
- Leaking container
- Slides broken beyond repair
Fluorescence in situ hybridization (FISH)
Normal or Abnormal with interpretation.