Submit a formalin-fixed, paraffin embedded tissue

Formalin-fixed, paraffin embedded (FFPE) tissue block

FFPE tissue section mounted on a charged, unstained slide

Ambient (preferred)

• Unlabeled/mislabeled block
• Insufficient tissue
• Slides broken beyond repair

Immunohistochemical staining and microscopic examination

If requested, an interpretive report will be provided

Specifications

• The antibody reacts with a nuclear antigen which is expressed throughout the cell cycle (G1, S, G2, M phases)
• Ki-67 is never expressed by resting cells (in G0 phase)

Staining pattern

• Nuclear only

References

1. Gerdes et al: Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67. 1991, Am J Pathol, 4, 138, 8670873.
2. Al-Saleh W et al: Assessment of Ki-67 Antigen Immunostaining in Squamous Intraepithelial Lesions of the Uterine Cervix. Am J Clin Pathol 1995:104:154-160, 1995.