CD2 by IHC

Alphabetical Test listing

CD2 by IHC-12376 - Technical only, 12379 - Technical & interpretation

Test name:

CD2 by IHC

Test number:

12376 - Technical only, 12379 - Technical & interpretation

Excellian order number:

LAB12376
LAB12379

Tests included:

All IHC stains will include a positive control tissue

Useful for:

CD2 is a pan T-cell marker used to identify benign and malignant T lymphocytes
CD2 should be used in a panel with other T-cell markers

Specimen type:

Tissue

Processing instructions:

Submit a formalin-fixed, paraffin-embedded tissue

Transport container:

Formalin-fixed, paraffin-embedded (FFPE) tissue block

Alternate transport container:

FFPE tissue section mounted on a charged, unstained slide

Transport and stability:

Ambient (preferred)

Reason for rejection:

Unlabeled/mislabeled block
Insufficient tissue
Slides broken beyond repair

Performing lab:

AHL - Immunohistochemistry

Days set up:

Mo - Fr

TAT:

1 - 2 days

Method:

Immunohistochemical staining and microscopic examination

Reference ranges:

If requested, an interpretive report will be provided

Clinical information:

Specifications

CD2 is a glycoprotein found on most peripheral T-lymphocytes, on a subset of NK lymphocytes and on cortical thymocytes
Some thymic B-lymphocytes are also positive for CD2
CD2 is the E-rosette receptor.

Staining pattern

Cell surface membrane staining

References

Malisius R, et al: Constant detection of CD2, CD3, CD4, and CD5 in fixed and paraffin-embedded tissue using the peroxidase-mediated deposition of biotin-tyramide. J. Histochem Cytochem 1997; 45: 1665-1672.

CPT codes:

88342 - 1st stain
88341 - each additional stain

Date created:

10/30/2017

Revised date:

10/17/2018

Review date:

01/12/2024