Haptoglobin
Haptoglobin-127
Haptoglobin binds hemoglobin which is released during erythrocyte lysis. The haptoglobin/hemoglobin complex is rapidly eliminated from the bloodstream. Increased release of hemoglobin due to intravascular hemolysis results in a reduction in the haptoglobin concentrations, and during severe hemolysis, to complete consumption of the haptoglobin. In children, haptoglobin has lower physiological concentrations and therefore is not suited for hemolysis testing. Haptoglobin is an acute-phase protein which can develop very high levels during inflammatory conditions.
Immediately following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting
Spin within two (2) hours of sample collection
Lt green plasma separator (PST)
Immediately following collection, mix sample by gently inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Spin within two (2) hours of sample collection
Gold serum separator (SST) tube
Ambient - 3 months
- Improper labels (unlabeled or mislabeled)
- Hemolysis (some procedures)
- Improper anticoagulant or ratio
- Delay in transport
- Improper storage temperature affecting results
- Improper container
- Leaking container resulting in compromised specimen
- Quantity not sufficient (QNS)
Immunoturbidometric
30 - 200 mg/dL