C-telopeptide

Alphabetical Test listing

C-telopeptide-14230

  
C-telopeptide
  
14230
  
LAB14230
  
CTELOPEP
  
Beta-CTX
Beta Crosslaps
Carboxyterminal Cross-linking Telopeptide of Bone Collagen
Collagen Cross-linked C-Telopeptide
Crosslaps
CTX
Type 1 Collagen
  
  • For in vitro diagnostic use as an indicator of human bone resorption.
  • This test may be used as an aid in monitoring bone resorption changes of antiresorptive therapies in postmenopausal women, individuals with osteopenia, and in predicting skeletal response (bone mineral density) in postmenopausal women undergoing antiresorptive therapies.
  • Hormone replacement therapies (HRT) with hormones and hormone-like drugs
  • Bisphosphonate therapies
  
  • Biotin, commonly found in hair, skin and nail supplements and multivitamins, may interfere with assay. Patients should be cautioned to stop biotin consumption at least 72 hours prior to sample collection.
  • It is recommended to draw blood as fasting, morning samples.
  
Serum
  

Gold serum separator (SST) tube

  
0.5 mL
  
0.3 mL
  

Immediately following collection, thoroughly mix sample by gently inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within 45 minutes of sample collection
  3. Transfer serum to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as serum
  4. Freeze
  

Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp)

  

Frozen (preferred) - 3 months

Freeze/thaw cycles - stable x6

Refrigerated - 2 days

Ambient - 6 hours

  
LabCorp Endocrine Sciences (500089): R-LC
  
Mo - Fr
  
3 - 5 days
  

Electrochemiluminescence immunoassay (ECLIA)

  

Male: 38 - 724 pg/mL

Female:

Premenopausal: 34 - 635 pg/mL

Postmenopausal: 34 - 1037 pg/mL

  
Biotin interference - see Patient preparation
  
82523
  
Yes
  

Medical necessity

  
05/02/2019
  
07/27/2026
  
07/27/2026