UroVysion by FISH (Bladder cancer)

Alphabetical Test listing

UroVysion by FISH (Bladder cancer)-4280Z

Test name:

Test number:

4280Z

Excellian order number:

LAB4280Z - CYTOGENETIC FISH UROTHELIAL CARCINOMA

Abbreviation:

CG UFISH

Alternate names:

Aneuploidy 3, 7, 17, deletion 9p21, homozygous loss of p16 gene
Bladder Cancer
Cytology reflex FISH
Upper Urinary Tract Cancer
Urothelial Carcinoma
UroVysion

Useful for:

Detection of aneuploidy changes associated urothelial carcinoma involving the bladder or upper urinary tract

Specimen type:

Urine, random (voided or catheterized)

Collection container:

Screw cap plastic container (sterile)

Volume:

30 mL

Collection instructions:

Voided urine specimens should be clean catch

Processing instructions:

Submit entire specimen

The addition of a preservative is necessary if a delay in transport may occur. Acceptable preservatives include: 70% ethanol, Carbowax, PreservCyt, CytoLyt, Cytorich Red or Clear, PreservCyt.

Transport container:

Screw cap plastic container (sterile)

Alternate specimen type:

Washings such as bladder, kidney, ureter, and renal
Urinary stoma

Required forms/information:

Cytogenetics oncology request

Transport and stability:

Ambient - 24 hours

Refrigerate if not sending the same day.

Specimen retention time:

Slides - 6 months

Reason for rejection:

Over-abundant contamination
Improper label (unlabeled or mislabeled)
Delay in transport
Improper storage
Leaking container

Performing lab:

AHL - Cytogenetics: X

Days set up:

As needed

TAT:

5 days

Method:

Fluorescence in situ hybridization (FISH)

Reference ranges:

Polysomy, Homozygous 9p21 Loss, Tetraploidy, Negative

CPT codes:

88120 – Urine FISH

This test includes a charge for application of the 4 FISH probes and professional interpretation of the results. If no cells are available for analysis, no analysis charges will be incurred.

Date created:

03/07/2016

Revised date:

03/11/2021

Review date:

04/06/2021