Carbamazepine sensitivity HLA associations
Carbamazepine sensitivity HLA associations-994
HLA A*3101
HLA A*31:01
HLA A3101
HLA B*1502
HLA B*15:02HLA B1502
Oxcarbazepine Sensitivity
To avoid possible adverse reactions, this test has been recommended for patients who may be prescribed Carbamazepine and oxcarbazepine. Two HLA alleles are associated with adverse reactions to these drugs. The alleles are HLA B*15:02, which is more common in individuals of Asian descent, and HLA A*31:01, which is more common in individuals of European descent. This test evaluates the presence or absence of these alleles.
Immediately following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting
Lavender (EDTA), 4mL
Molecular Medicare billing request
Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.
Ambient (preferrred)
Refrigerated (OK)
Insufficient volume of DNA
Next Generation Sequencing (NGS), sequence-based typing (SBT), sequence-specific oligonucleotide probes (SSOP) and/or sequence-specific primers (SSP) as needed to obtain the required resolution
Negative
A negative test result does not rule out an adverse reaction with the drug Carbamazepine and oxcarbazepine
Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.