Therapeutic drug management
Trough levels are most reproducible
Dk green heparin (Li or Na), no gel
Immediately following collection, mix sample by inverting 5 - 10 times to prevent clotting.
Refrigerated (preferred)
Ambient - 3 days
Frozen - (OK)
Gel-barrier tubes are not recommended
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
10.0 - 80.0 ng/mL
Plasma concentrations of olanzapine greater than 9.0 ng/mL have been associated with therapeutic effect
Not established