ACHE, amniotic fluid, with reflex to Hb F

Alphabetical Test listing

ACHE, amniotic fluid, with reflex to Hb F-13503

Test name:

Test number:

13503

Excellian order number:

LAB13503

Abbreviation:

ACHE

Alternate names:

AChE
Amniotic Fluid With Reflex to Hb F
Acetylcholinesterase (AChE), amniotic fluid w/ reflex to fetal hemoglobin (Hb F)

Useful for:

Analysis of midtrimester amniotic fluid for detection of open neural tube defects and ventral wall defects

Patient preparation information:

The patient's gestational age must be at least 13 weeks for accurate AChE detection
Optimal gestational age is 14 to 18 weeks

Specimen type:

Amniotic fluid

Collection container:

Sterile vial/container

Volume:

3.0 mL

Minimum volume:

3.0 mL

Collection instructions:

Avoid contamination of amniotic fluid with maternal or fetal blood. As little as one drop of fetal blood can cause false-positive results during assay of amniotic fluid.

Transport container:

Sterile vial/container.

Do NOT use urine containers or tubes with rubber stoppers; rubber is toxic to amniocytes.

Required forms/information:

Gestational age by ultrasound and/or last menstrual period (LMP)

Transport and stability:

Ambient

Reason for rejection:

Specimen found not to be amniotic fluid
Gross contamination of amniotic fluid with maternal or fetal blood
Quantity not sufficient for analysis (QNS)

Performing lab:

LabCorp RTP (510354): R-LC

Days set up:

3x/week

TAT:

8-14 days

Method:

Acrylamide gel electrophoresis
Isoelectric focusing (IEF)

Reference ranges:

Negative

CPT codes:

82013

Date created:

03/27/2019

Revised date:

06/26/2019

Review date:

01/02/2024