Detect neutralizing antibodies to poliovirus (types 1 and 3).
Immediately following collection, thoroughly mix sample by gently inverting 5 times
Gold serum separator (SST) tube
Refrigerated (preferred) - 2 weeks
Ambient – 48 hours
Frozen – 1 year
Semi-quantitative serum neutralization
< 1:10 |
No detectable poliovirus antibodies. |
≥ 1:10 |
Antibody to poliovirus detected, which may represent prior immunization or current or past infection. |
The presence of neutralizing antibodies against poliovirus implies immunity. The serum neutralization test is serotype specific. Antibodies against one type does not indicate immunity against the other type.