Isoniazid, serum or plasma

Alphabetical Test listing

Isoniazid, serum or plasma-994

Test name:

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

Nydrazid

Useful for:

Therapeutic drug management

Specimen type:

Serum

Collection container:

Red serum vial/tube, 5 mL

Volume:

2.0 mL

Minimum volume:

0.5 mL

Collection instructions:

Trough levels are most reproducible

Processing instructions:

Allow sample to clot
Spin within two (2) hours of sample collection
Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum

Transport container:

Transfer vial/tube with cap - 12 mL (LabCorp)

Alternate specimen type:

Heparin plasma

Alternate collection container:

Dk green heparin (Li or Na), no gel

Alternate collection instructions:

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times, to prevent clotting

Alternate processing instructions:

Spin within two (2) hours of sample collection
Transfer plasma to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as the appropriate plasma type

Alternate transport container:

Transfer vial/tube with cap - 12mL (LabCorp)

Transport and stability:

Refrigerated (preferred)

Ambient - <3 days

Frozen (OK)

Reason for rejection:

Gel-barrier tubes are not recommended

Performing lab:

MedTox Laboratories Inc via LabCorp (808376): R-NX

Days set up:

TAT:

10 - 14 days

Method:

High-pressure liquid chromatography with ultraviolet detection (HPLC/UV)

Reference ranges:

The effective concentration range of isoniazid is dependent on the minimum inhibitory concentration of the pathogen being treated.

Results that require action (critical):

Toxic range: >20 µg/mL

CPT codes:

80299

Date created:

01/30/2020

Review date:

01/03/2024