Anti-cN-1A Ab (NT5c1A) IBM (RDL)
Anti-cN-1A Ab (NT5c1A) IBM (RDL)-994
IBM
Inclusion body myopathy
MUP44 AB
nt5c1a
sIBM
Sporadic IBM
Anti-cN-1A autoantibodies in idiopathic inflammatory myopathy (IIM) patients appear to be disease-specific for sporadic Inclusion Body Myositis (sIBM) and are rarely detected in other autoimmune conditions. Anti-cN-1A autoantibodies have a moderate sensitivity, but their high specificity for sIBM may be helpful in the diagnosis of this infrequent and difficult-to-diagnose myopathy. This assay can augment and accelerate the suspected diagnosis of sIBM using sera where muscle biopsy is delayed and/or unfeasible.
(Note: This volume does not allow for repeat testing.)
Immediatley following collection, mix sample by gently inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Spin within one (1) hour of sample collection
Gold serum separator (SST) tube
- Allow sample to clot for a minimum of 30 minutes
- Spin within one (1) hour of collection
- Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum
Refrigerated (preferred) - 14 days
Ambient - 7 days
Frozen - 60 days
Freeze/thaw cycles - stable x1
- Grossly hemolyzed
- Bacterial contamination
- Lipemic specimen
- Icteric specimen
- Non-serum specimen types
Enzyme-linked immunosorbent assay (ELISA)
Negative: <20