Trofile®

Alphabetical Test listing

Test name:

Trofile®

Test number:

13573

Excellian order number:

LAB13573

Abbreviation:

TROFILE

Alternate names:

CCR5
Chemokine co-receptor tropism
Co-Receptor Tropism (phenotypic)
CXCR4
HIV
Monogram Biosciences
Tropism

Useful for:

Detect HIV-1 co-receptor tropism
Determine eligibility for CCR5 antagonist therapy such as maraviroc (Selzentry^TM)

Limitations:

This test should be used for patients with documented HIV-1 infection and viral loads ≥1000 copies/mL

Specimen type:

EDTA plasma

Collection container:

Volume:

3.0 mL

Collection instructions:

Collect specimen in two (2) Lavender (EDTA), 4mL tubes
Immediatley following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting

Processing instructions:

Spin
Transfer plasma to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as EDTA plasma, within six (6) hours of sample collection
Freeze within six hours of sample collection

Transport container:

Transport and stability:

Frozen (strict)

Reason for rejection:

Performing lab:

Monogram Biosciences (E3100) via LabCorp (553100): R-LC

TAT:

35 days

Method:

Polymerase Chain Reaction (PCR) amplification and viral culture

Reference ranges:

An interpretive report will be provided

LOINC code:

Result 51969-4

Date created:

04/08/2019

Revised date:

04/13/2022

Review date:

04/12/2022