Anti-Granulocyte-macrophage colony-stimulating factor (GMCSF) autoantibodies

Alphabetical Test listing

Anti-Granulocyte-macrophage colony-stimulating factor (GMCSF) autoantibodies-994

Test name:

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

GM-CSF
PAP
GMCSFA
Granulocyte monocyte-colony stimulating factor antibodies
Pulmonary alveolar proteinosis
Intracellular infection

Useful for:

The GM-CSF ELISA assay detects auto-antibodies to granulocyte-macrophage colony stimulating factor (GM-CSF). If positive, will reflex with a validated flow cytometry assay that measures the ability of the autoantibody to neutralize GM-CSF mediated responses.

Specimen type:

Serum

Collection container:

Gold serum separator (SST) tube

Red serum vial/tube - 5 mL

Volume:

1.0 mL

Minimum volume:

0.5 mL

Collection instructions:

Immediately following collection, mix sample by gently inverting 5 times.

Processing instructions:

Allow sample to clot for a minimum of 30 minutes
Spin within two (2) hours of sample collection
Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum

Transport container:

Transfer vial/tube with cap - 12mL (LabCorp)

Transport and stability:

Frozen (preferred) - >1 month

Refrigerated - 48 hours

Ambient - NO

Reason for rejection:

Clotted specimens
Hemolyzed specimens
Plasma specimens

Performing lab:

National Jewish Health (GMCSE) via LabCorp (009985)

Days set up:

Mo - Fr

TAT:

14 days

Method:

ELISA followed by confirmation by flow cytometry

Reference ranges:

Negative

CPT codes:

83516, 86353, 88184, 88185

Date created:

01/06/2026

Review date:

01/06/2026