Dehydroepiandrosterone (DHEA), serum
Dehydroepiandrosterone (DHEA), serum-13320
Evaluate adrenal carcinomas which frequently secrete large amounts of Dehydroepiandrosterone (DHEA).
Submission of the minimum volume does not allow for repeat testing
Immediately following collection, thoroughly mix sample by gently inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Spin within two (2) hours of sample collection
- Transfer serum to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as serum
- Freeze
- Allow sample to clot
- Spin
- Transfer serum to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as serum, within two (2) hours of sample collection
- Freeze
Frozen (preferred) - 14 days
Freeze/thaw cycle stability x 3
Refrigerated - 14 days
Ambient - 6 hours
Liquid chromatography tandem/mass spectrometry (LC/MS-MS)
|
Age |
Ref range (ng/dL) |
|
0 – 5 years |
0 − 67 |
|
6 – 7 years |
0 − 110 |
|
8 – 10 years |
0 − 185 |
|
11 – 12 years |
0 − 201 |
|
13 – 14 years |
0 − 318 |
|
15 – 16 years |
39 − 481 |
|
17 – 19 years |
40 − 491 |
|
20 - 50 years |
31 − 701 |
|
> 50 years |
21 - 402 |
DHEA is a steriod which is produced by both the adrenal cortex and testis. The levels of this steriod increase before the onset of puberty (adrenarche), and decrease significantly with age. DHEA and DHEA-S are the major precursors of 17-ketosteroids.