Porphobilinogen Deaminase, Whole Blood

Alphabetical Test listing

Porphobilinogen Deaminase, Whole Blood-994

Test name:

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

PBG Deaminase
Acute intermittent porphyria
AIP
HMBS (Hydroxymethylbilane synthase)
Hydroxymethylbilane synthase (HMBS)
Uroporphyrinogen I synthase

Useful for:

Confirmation of a diagnosis of acute intermittent porphyria

Patient preparation information:

Patient should abstain from alcohol for 24 hours prior to specimen collection

Specimen type:

Sodium heparin (Na hep) whole blood

Collection container:

Dk green Sodium heparin (Na hep), no gel

Volume:

4 mL

Minimum volume:

3 mL

Collection instructions:

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times to prevent clotting

Processing instructions:

Do not spin
Submit original tube (do not open)
Refrigerate as soon as possible

Transport container:

Dk green Sodium heparin (Na hep), no gel

Alternate specimen type:

EDTA whole blood
Lithium heparin (Li hep) whole blood

Alternate collection container:

Lavender (EDTA), 4mL

Dk green Lithium heparin (Li hep) tube, no gel

Required forms/information:

Include a list of medications patient is currently taking

Transport and stability:

Refrigerated (strict) - 8 days

Ambient - 7 days

Frozen - NO

Reason for rejection:

Gross hemolysis

Performing lab:

Mayo Clinic Laboratories (PBGD): R-NX

Days set up:

TAT:

2 - 8 days

Method:

Enzymatic End Point/Spectrofluorometric

Reference ranges:

≥ 7.0 nmol/L/sec

CPT codes:

82657

Date created:

12/11/2007

Revised date:

07/23/2025

Review date:

07/23/2025