BCL6 by FISH

Alphabetical Test listing

BCL6 by FISH-4280J

Test name:

BCL6 by FISH

Test number:

4280J

Excellian order number:

LAB4280J - CYTOGENETICS MALIGNANT TISSUE STUDIES

Abbreviation:

CG BCL6 or BCL6

Alternate names:

BCL6
Diffuse large B-cell lymphoma
FISH
Fluorescence in situ hybridization
High grade B-cell lymphoma
Large B-cell lymphoma
3q27

Useful for:

BCL6 rearrangements are associated with Large B-cell lymphoma and can help differentiate diffuse Large B-cell lymphoma from High-grade lymphoma.

This test can be ordered individually or as part of a High Grade Lymphoma FISH Panel. See the panel test for details.

Specimen type:

Solid Tumor or aspirate/Lymph Node (fresh tissue)

Collection container:

Sterile cup or tube

Volume:

5 mm³
5 mL

Collection instructions:

Specimens should be immersed in sterile culture medium, sterile Hanks Balance Salt Solution (HBSS) or sterile saline.

Processing instructions:

Submit entire fresh specimen.

Transport container:

Sterile culture medium or in a sterile cup with sterile saline

Alternate specimen type:

Paraffin embedded tissue
Slides
Touch prep slides

Alternate collection container:

Paraffin block

Three 4-micron cut slides and one H&E stained slide

Touch prep slides

Note: Heavy metal fixatives are unacceptable.

Required forms/information:

AHL Cytogenetics Oncology Request

Transport and stability:

Ambient

Specimen retention time:

Slides - 6 months
Blocks will be returned post reporting

Reason for rejection:

Improper label (unlabeled or mislabeled)
Slides broken beyond repair
Heavy metal fixatives are unacceptable

Performing lab:

AHL - Cytogenetics: X

Days set up:

Mo - Fr

TAT:

5 business days

Method:

Fluorescence in situ hybridization (FISH)

Reference ranges:

Normal or Abnormal with interpretation

CPT codes:

Paraffin:
88366 x 2
Fresh Tissue/Touch Prep:
88271 x 2
88275
88291

Subject to medical necessity (Y/N):

Yes

LCD/NCD:

Medical necessity

Date created:

03/26/2021

Revised date:

09/14/2022