Certolizumab and anti-Certolizumab antibody

Alphabetical Test listing

Certolizumab and anti-Certolizumab antibody-15273

Test name:

Test number:

15273

Excellian order number:

LAB15273

Abbreviation:

CERTO

Alternate names:

Anti-TNF
Anti-TNF drug
Biologic drug level and anti-drug antibody
Biologic monitoring

Cimzia
DoseASSURE
Immunogenicity testing
TDM
TNF inhibitor

Tests included:

Certolizumab drug level, anti-certolizumab antibodies and serial monitoring

Useful for:

Provides certolizumab drug concentration and anti-certolizumab antibodies in order to optimize treatment and facilitate clinical decision-making. This assay may be helpful in any patient on certolizumab therapy for Crohn's disease, psoriasis, or other autoimmune condition.

Specimen type:

Serum

Collection container:

Gold serum separator (SST) tube

Red serum vial/tube - 5 mL

Volume:

2.0 mL

Minimum volume:

0.6 mL

Collection instructions:

Immediately following collection, mix sample by gently inverting 5 times

Processing instructions:

Allow sample to clot for a minimum of 30 minutes
Spin within two (2) hours of sample collection
Transfer serum to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as serum
Freeze

Transport container:

Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp)

Transport and stability:

Frozen (preferred) - 14 days

Refrigerated - 14 days

Ambient - 18 hours

Freeze/thaw cycles: stable x 6

Reason for rejection:

Gross hemolysis
Gross lipemia

Performing lab:

Esoterix Endocrinology (804627) via LabCorp (504627) : R-LC

Days set up:

TAT:

8 - 15 days

Method:

Electrochemiluminescence Immunoassay (ECLIA); Surface Plasmon Resonance

Reference ranges:

An interpretive report will be provided

CPT codes:

80299
82397

Date created:

08/29/2019

Revised date:

06/25/2024

Review date:

06/25/2024