HLA-A29 Uveitis
HLA-A29 Uveitis-994
A29
Birdshot Chorioretinopathy
Birdshot retinochoriodopathy
BSRC
HLA A29
HLA-A29
Birdshot chorioretinopathy (BSCR) is a rare form of autoimmune uveitis that can lead to severe visual impairment. Greater than 95% of patients diagnosed with BSCR carry the human leukocyte antigen (HLA)A*29 allele of the major histocompatibility complex (MHC). The MHC family of genes code for a highly variable set of cell surface glycoproteins (HLAs) that play a critical role in presenting antigens to T cell receptors to elicit an immune response.
Immediately following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting
Lavender (EDTA), 10mL
Two (2) Lavender (EDTA), 4mL
Two (2) Lavender (EDTA), 4mL
Molecular Medicare billing request
Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.
Ambient (strict) – 7 days
Frozen – NO
Refrigerated - NO
- Hemolysis
- Clotted specimen
HLA results are obtained using Next Generation Sequencing (NGS). Supplemental procedures based on Sanger sequence based typing (SBT) may be used as needed to obtain the required resolution.
See report
The presence of HLA A*29 alone is not sufficient for a diagnosis of Birdshot Chorioretinopathy. Many individuals with HLA A*29 do not have the disease and some patients with the disease do not have HLA A*29.
Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.