CD31 by IHC

Alphabetical Test listing

CD31 by IHC-12376 - Technical only, 12379 - Technical & interpretation

Test name:

CD31 by IHC

Test number:

12376 - Technical only, 12379 - Technical & interpretation

Excellian order number:

LAB12376
LAB12379

Alternate names:

Anti-human endothelial cell

Tests included:

All IHC stains will include a positive control tissue

Useful for:

CD31 is a very sensitive and specific marker for endothelial differentiation, and is probably the first choice for vascular markers in studying benign and malignant vascular tumors
CD31 reacts weakly with mantle zone B cells, peripheral T cells, and neutrophils
In cryostat sections and blood smears, CD31 also labels megakaryocytes, platelets, and some plasma cells

Specimen type:

Tissue

Processing instructions:

Submit a formalin-fixed, paraffin-embedded tissue

Transport container:

Formalin-fixed, paraffin-embedded (FFPE) tissue block

Alternate transport container:

FFPE tissue section mounted on a charged, unstained slide

Transport and stability:

Ambient (preferred)

Reason for rejection:

Unlabeled/mislabeled block
Insufficient tissue
Slides broken beyond repair

Performing lab:

AHL - Immunohistochemistry

Days set up:

Mo - Fr

TAT:

1 - 2 days

Method:

Immunohistochemical staining and microscopic examination

Reference ranges:

If requested, an interpretive report will be provided

Clinical information:

Specifications

Reacts with a glycoprotein found in endothelial cells and platelets

Staining pattern

Cytoplasmic and cell membrane-based staining

References

De Young and Wick, et. al.: CD31: An Immunospecific Marker for Endothelial Differentiation in Human Neoplasms; Appl. Immunohistochem. 1:97-100, 1993.
Longacre et. al.: CD31: A New Marker for Vascular Neoplasia; Advances in Anat. Pathol. 1:16-20, 1994.

CPT codes:

88342 - 1st stain
88341 - each additional stain

Date created:

06/16/2017

Revised date:

10/17/2018

Review date:

01/12/2024