4Kscore (Kit Test)

Alphabetical Test listing

4Kscore (Kit Test)-12636

  
4Kscore (Kit Test)
  
12636
  
LAB12636
  
4K score
4K prostate screen
4K Prostate Score
Kallikrein score
Four K
Cancer Genetic MSO
  

The 4Kscore Test calculates the risk for aggressive prostate cancer by measuring several proteins in the blood and combining that with clinical findings.

It can be used after an abnormal PSA result if considering a prostate biopsy.

  

This order is for Allina Health providers only

4Kscore Test is not indicated for men if:

  • Previous diagnosis of prostate cancer
  • Younger than 45 years of age
  • Within 96 hours after a digital rectal examination
  • Receiving 5-alpha reductase inhibitors (5ARIs) therapy within the previous 6 months
  • Undergone any significant, invasive urological procedure or therapy that may be associated with secondary PSA elevation within the prior 6 months
  

Patient must present with a completed requisition

  
Serum
  

Speckled top Serum separator tube (SST) X 2 

Kit/specialty tubes must be requested from the Central lab supply prior to patient arriving in the lab

  
4 mL
  

Immediately following collection, mix sample thoroughly by gentle inversion, 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Speckled top serum separator tubes (SST)

  

4Kscore test requisition- to be completed by the provider 

 

  

Refrigerated - 72 hours

Time sensitive: Specimens should be collected Monday – Thursday. Specimens must be received at the Central lab by 1pm.

**SPECIMEN MUST BE SHIPPED WITHIN 24HRS OF COLLECTION**

  
BioReference Laboratories (J148-8)
  
Mo- Fr
  
3 days
  

Electrochemiluminescence Immunoassay

  

An interpretive report will be sent directly to the provider

  

The 4Kscore test result is the probability of finding high-grade, aggressive prostate cancer (Gleason 7 or higher) if a prostate biopsy were to be performed.

A 4Kscore <5.0 is associated with decreased likelihood of a Gleason score ≥7 on biopsy. Prostate biopsy is required for the diagnosis of cancer. The test is not recommended more than once every 6 months.

  
BioReference Laboratories is responsible for billing
  
07/20/2022
  
02/12/2026
  
02/12/2026